Use of 15-Valent Pneumococcal Conjugate Vaccine Among U.S. Children... - CDC
Evidence Pneumococcal Disease Incidence in Persons Aged <19 Years Acute otitis media is one of the most common diagnoses associated with outpatient pediatric medical visits ( 8 ) and antibiotic prescribing ( 9 ). According to a recent analysis using administrative data, 20,800 all-cause acute otitis media episodes per 100,000 person-years occurred among U.S. persons aged <18 years during 2018, with a higher incidence in younger age groups ( 10 ). During 2015–2019, in a cohort of 319 U.S. children aged 6–36 months with clinically diagnosed acute otitis media, Streptococcus pneumoniae was detected in the middle ear fluid of 24% ( 11 ); 9% of these children were infected with a PCV13 serotype (including 6C), and 8% with one of the serotypes included in PCV15 but not in PCV13 (serotypes 22F and 33F) ( 11 ). Additional analysis using administrative data estimated that among persons aged <18 years, 1,280 to 3,990 episodes of health care utilization per 100,000 perso...