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Showing posts from February, 2023

Bioengineered materials with selective antimicrobial toxicity in ... - Military Medical Research

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Hernando-Amado S, Coque TM, Baquero F, Martínez JL. Defining and combating antibiotic resistance from one health and global health perspectives. Nat Microbiol. 2019;4(9):1432–42. Article  CAS  PubMed  Google Scholar  Ellabaan MMH, Munck C, Porse A, Imamovic L, Sommer MOA. Forecasting the dissemination of antibiotic resistance genes across bacterial genomes. Nat Commun. 2021;12(1):2435. Article  CAS  PubMed  PubMed Central  Google Scholar  Zafar H, Yousefiasl S, Raza F. T-cell membrane-functionalized nanosystems for viral infectious diseases. Mater Chem Horizons. 2023;2(1):41–8. Google Scholar  Abedon ST. Bacterial 'immunity' against bacteriophages. Bacteriophage. 2012;2(1):50–4. Article  PubMed  PubMed Central...

Perforated Appendicitis Presenting as a Soft Tissue Infection of the ... - Cureus

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Global spread of vaccine-derived polio still a high risk: WHO - Down To Earth Magazine

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Recommends declaring transmission as a national public health emergency, ensuring vaccinations for travellers and residents The WHO panel reviewed the data on wild poliovirus (WPV1) and circulating vaccine-derived polioviruses (cVDPV) for the global target of WPV eradication and cessation of cVDPV2 outbreaks by the end of 2023. Photo: iStock The risk of global spread of poliovirus remains a public health emergency of international concern, a  World Health Organization committee has found  after looking into updates from 10 countries. While the risk of global spread of wild poliovirus remains, the risk of circulating vaccine-derived ones is higher.  Several measures like declaring poliovirus transmission as a national public health emergency and ensuring vaccinations for travellers and residents ha...

Why does it feel like everyone is sick at the moment? - Gavi, the Vaccine Alliance

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It was the bout of norovirus that nearly made me lose my sanity, coming as it did on the heels of weeks of severe respiratory illness. After developing pneumonia in mid-January, I tried to isolate myself from my daughter when she then caught a chest infection that sounded like marbles were rattling in her lungs, but small children tend to cling, koala-like, to their parents when they are sick. As my own immune system was already battered, I caught her infection too. The subsequent gastrointestinal bug was the cherry on this particularly horrendous cake. There is a danger that "the immunity debt theory is being used to spread misinformation and promote a dangerous theory that natural infections are better than vaccines." Winter sniffles are not an uncommon seasonal occurrence, and they are a regular feature in our home as I'm asthmatic and have a homemade germ factory with a primary school age kid. But this recent bout of illness has been unusually brut...

Mpox Often Leads to Severe Illness, Even Death, in People With Advanced H.I.V. - The New York Times

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The death rate among these patients is about 15 percent, researchers reported. The virus should be added to the list of opportunistic infections seen in patients with advanced H.I.V., scientists said. In people with advanced H.I.V. disease, the mpox virus — formerly known as monkeypox — often causes severe illness, with a death rate of about 15 percent, researchers reported on Tuesday. The seriousness of the infection warrants the inclusion of mpox among the opportunistic conditions that are particularly dangerous to people with advanced H.I.V., the researchers said at the Conference on Retroviruses and Opportunistic Infections in Seattle. "These findings make it very, very clear that every single person with mpox should have an H.I.V. test," said Dr. Chloe Orkin, an H.I.V. expert at Queen Mary University of London and the researcher who led the work. She and her colleagues also described the results in the journal The Lancet on Tuesday. The mpox outbreak began unfolding last...

How to Get Rid of Impetigo: Treatment Options - Everyday Health

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Oza says if the impetigo is confined to a small area and doesn't seem to go deep into the skin, he'd recommend treating the area with a topical antibiotic. Unfortunately, while over-the-counter options can be helpful to apply to abrasions in the skin to lessen the chances of impetigo developing, they won't do much to heal the impetigo itself. (3) Instead, a doctor will likely recommend a topical antibiotic, such as ozenoxacin (Xepi), mupirocin (Bactroban), retapamulin (Altabax), or fusidic acid. (1) It should be applied directly to the sores on the body. Your doctor might suggest soaking the scab first so the antibiotic can really get down into the skin. (4) The goal is to keep the impetigo contained and prevent it from spreading to other parts of the body and to other family members in the household. That's where good hygiene comes into play. Be diligent about thoroughly cleaning towels and sheets, for instance, to reduce the risk of impetigo spreading, Oza says. Set t...

Ecoza (Econazole) – Topical: Uses, Side Effects, Dosages - Verywell Health

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What Is Ecoza? Ecoze (econazole) is an azole antifungal topical medication used to treat certain fungal infections of the skin. Econazole blocks a fungal protein called cytochrome P-450-mediated 14 alpha-lanosterol demethylase enzyme. By inhibiting this fungal protein, econazole prevents lanosterol—a type of steroid—from converting to ergosterol . Ergosterol is important in forming the fungal cell wall. So, econazole works by interfering with the structure of the fungal cell wall. Econazole is available as a topical cream (generic econazole) or as a foam (under the brand name Ecoza). It can be used to treat infections such as: Drug Facts Generic name :   Econazole Brand name(s) : Ecoza Drug availability : Prescription Administration route :   Topical Therapeutic classification :   Antifungal Available generically :   Yes Controlled substance :   N/A Active ingredient :   Econazole...